Thermostability of Bacillus cereus Penicillinase

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Properties of penicillinase from Bacillus cereus 569.

Penicillinase from Bacillus cereu.s 569 was purified and examined for homogeneity by sedimentation analysis, aminoterminal analysis, and vertical acrylamide gel electrophoresis. The enzyme preparation was shown to contain three distinct species of extracellular penicillinase which could be separated easily by gel electrophoresis. Kinetic studies failed to reveal any significant differences in t...

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The cell-bound penicillinase of Bacillus cereus.

Only 30-50 yo of the cell-bound penicillinase of Bacillus cereus NRRL 569 is neutralized by antiserum prepared against the exo-penicillinase. The unneutralizable fraction is not decreased by cell disintegration which liberates a proportion of the cell-bound enzyme into solution. Absence of neutralization cannot therefore be explained by the existence of a mechanical barrier which prevents acces...

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Purification of Penicillin - Induced Penicillinase of Bacillus cereus NRRL 569

We wish to express our thanks to Dr Melvin Cohn for much valuable advice during the preliminary work on methods of purification, and one of us (M.R.P.) is greatly indebted to Dr Jacques Monod of the Institut Pasteur, Paris, for the hospitality of his laboratory in which much of the earlier work on isolation ofpenicillinase was carried out. We are also grateful to Dr T. S. Work for help in the c...

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Metabolic Control of Penicillinase Biosynthesis in Bacillus Cereus.

Yip, Lily C. (University of Cincinnati, Cincinnati, Ohio), Ramesh Shah, and Richard A. Day. Metabolic control of penicillinase biosynthesis in Bacillus cereus. J. Bacteriol. 88:297-308. 1964.-Penicillinase production in strains 5 and 5/B of Bacillus cereus in response to treatment by 6-aminopenicillanic acid (APA), penicillin G, (6-N-alpha-(p-benzyloxyphenoxy)-propionylamino-penicillanic acid, ...

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Interconversion of a - and y - Penicillinase from Bacillus cereus 569

Extracellular penicilhnase from Bacillus cereus 569 was found to exist in two states, an iodine-sensitive state and an iodine-insensitive state. Iodine-sensitive penicillinase is inactivated by 2.5 X 10-a M iodine within 1 min, while the iodine-insensitive enzyme is inactivated at a much slower rate. Approximately 20% of the extracellular penicillinase activity found in crude or partially ptied...

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ژورنال

عنوان ژورنال: Journal of Bacteriology

سال: 1966

ISSN: 0021-9193,1098-5530

DOI: 10.1128/jb.91.1.257-261.1966